Alprostadil is combined with prostaglandin e1 as an injection with the trade name Caverject. It was introduced in 1996 and is used for the treatment of impotence. An injection is given into the penis, about one third the way from the base, at the 2 o’clock or 10 o’clock position. An erection usually occurs within ten minutes.
Side effects may include pain and bruising at the injection site, and a prolonged erection. It should not be used in patients taking anticoagulants or with any infection in the blood or groin.