Paget’s Disease – Hydroxy-proline/Creatinine Ratio

The ratio between the chemicals hydroxyproline and creatinine in blood can be measured. The normal level is less than 0.02.

High levels may indicate:

The ratio is a measure of the bone breakdown rate and calcium loss.

Calcium supplementation lowers the ratio after menopause.

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(Last modified: 17th Oct 2014)

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