The urethral syndrome is an inflammation of the bladder or urethra (tube leading to the outside from the bladder) without any infection being present. It causes discomfort on passing urine and increased frequency of passing urine. Investigations on the urine are all negative.
Urethral syndrome may be caused by minor injury to the urethra during sexual intercourse, bladder tumours, or a prolapse or irritation of the skin immediately around the opening of the urethra.
Treatment involves ceasing sexual activities for a few weeks, taking urinary alkalinisers and sometimes a trial of antibiotics in case a low grade infection is present. Persistent cases need to be further investigated by cystoscopy (looking into the bladder through a fine tube).